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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERO1L
All Species:
24.85
Human Site:
Y178
Identified Species:
34.17
UniProt:
Q96HE7
Number Species:
16
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96HE7
NP_055399.1
468
54393
Y178
I
Q
S
P
E
A
E
Y
V
D
L
L
L
N
P
Chimpanzee
Pan troglodytes
XP_509950
468
54427
Y178
I
Q
S
P
E
A
E
Y
V
D
L
L
L
N
P
Rhesus Macaque
Macaca mulatta
XP_001103965
468
54383
Y178
I
Q
S
P
D
A
E
Y
V
D
L
L
L
N
P
Dog
Lupus familis
XP_547813
468
54343
Y178
I
Q
S
P
D
A
E
Y
V
D
L
L
L
N
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8R180
464
54066
D174
I
D
D
I
Q
S
P
D
A
E
Y
V
D
L
L
Rat
Rattus norvegicus
Q8R4A1
464
54000
D174
V
D
D
I
Q
S
P
D
A
E
Y
V
D
L
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515503
465
53870
Y175
I
Q
S
P
D
A
E
Y
V
D
L
L
L
N
P
Chicken
Gallus gallus
XP_421473
463
52908
D173
A
D
D
I
H
S
P
D
A
E
Y
V
D
L
L
Frog
Xenopus laevis
Q6DD71
465
53720
Y176
E
E
S
P
D
A
E
Y
V
D
L
L
K
N
P
Zebra Danio
Brachydanio rerio
Q7T3D1
489
56571
Q169
D
E
D
S
P
E
S
Q
Y
V
D
L
L
L
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3A6
483
55641
V188
A
E
E
D
F
C
I
V
D
D
H
E
E
G
S
Honey Bee
Apis mellifera
XP_623933
471
55049
Q180
W
Q
Q
Y
D
D
A
Q
D
N
F
C
V
K
E
Nematode Worm
Caenorhab. elegans
Q7YTU4
478
55136
E173
F
C
E
I
E
D
D
E
S
D
G
M
H
Y
V
Sea Urchin
Strong. purpuratus
XP_796844
897
101920
H604
F
C
E
K
E
D
E
H
S
G
D
V
E
Y
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9C7S7
469
53812
N198
S
Y
V
N
L
Q
L
N
P
E
R
Y
T
G
Y
Baker's Yeast
Sacchar. cerevisiae
Q03103
563
65014
L178
F
N
G
K
N
A
V
L
I
D
L
T
A
N
P
Red Bread Mold
Neurospora crassa
Q7SEY9
668
75589
Y177
G
A
S
S
K
G
D
Y
V
S
L
L
R
N
P
Conservation
Percent
Protein Identity:
100
99.5
98.7
96.3
N.A.
91.8
91.4
N.A.
84.6
77.7
70.9
62.1
N.A.
46.1
48.4
41.4
29.3
Protein Similarity:
100
99.5
99.3
97.8
N.A.
95.9
95.7
N.A.
90.1
85.4
83.9
75.4
N.A.
64.1
65.6
60.8
37.6
P-Site Identity:
100
100
93.3
93.3
N.A.
6.6
0
N.A.
93.3
0
73.3
13.3
N.A.
6.6
6.6
13.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
33.3
33.3
N.A.
100
20
86.6
20
N.A.
13.3
26.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
37.9
22.5
22.1
Protein Similarity:
N.A.
N.A.
N.A.
55.6
41.2
38
P-Site Identity:
N.A.
N.A.
N.A.
0
33.3
46.6
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
40
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
6
0
0
0
42
6
0
18
0
0
0
6
0
0
% A
% Cys:
0
12
0
0
0
6
0
0
0
0
0
6
0
0
0
% C
% Asp:
6
18
24
6
30
18
12
18
12
53
12
0
18
0
0
% D
% Glu:
6
18
18
0
24
6
42
6
0
24
0
6
12
0
6
% E
% Phe:
18
0
0
0
6
0
0
0
0
0
6
0
0
0
0
% F
% Gly:
6
0
6
0
0
6
0
0
0
6
6
0
0
12
0
% G
% His:
0
0
0
0
6
0
0
6
0
0
6
0
6
0
0
% H
% Ile:
36
0
0
24
0
0
6
0
6
0
0
0
0
0
0
% I
% Lys:
0
0
0
12
6
0
0
0
0
0
0
0
6
6
0
% K
% Leu:
0
0
0
0
6
0
6
6
0
0
48
48
36
24
18
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% M
% Asn:
0
6
0
6
6
0
0
6
0
6
0
0
0
48
6
% N
% Pro:
0
0
0
36
6
0
18
0
6
0
0
0
0
0
48
% P
% Gln:
0
36
6
0
12
6
0
12
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
6
0
6
0
0
% R
% Ser:
6
0
42
12
0
18
6
0
12
6
0
0
0
0
6
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
6
6
0
0
% T
% Val:
6
0
6
0
0
0
6
6
42
6
0
24
6
0
12
% V
% Trp:
6
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
0
6
0
0
0
42
6
0
18
6
0
12
6
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _